New York State’s 6 million acre Adirondack Park holds some of the most ecologically intact ecosystems in the United States. Most of the park remains relatively free of invasive species, which presents an exciting opportunity in conservation rarely seen anywhere else in the country. The Adirondack Park Invasive Plant Program (APIPP), a regional partnership of government and private organizations, was formed in 1998 to effectively manage invasive species at a landscape scale. For four years, APIPP’s Terrestrial Rapid Response Team has surveyed and managed infestations of eight priority terrestrial invasive species. Photo documentation and spatial mapping of sites treated show steep declines in both acres infested and percent cover. Out of 131 Phragmites sites treated since 2010, 32% had no signs of invasive plant recovery as of 2014 and many exhibited a significant re-emergence of native vegetation. A summary of strategies used, work accomplished and lessons learned will be presented.