On March 25, 2012, twenty-five people began a year-long adventure into the world of Indigenous eating. These individuals were selected by the Northern Michigan University Center for Native American Studies as research subjects for the Decolonizing Diet Project (DDP), an exploratory study of the relationships between humans and Indigenous foods of the Great Lakes Region. Data from this study provides insight into biological, cultural, and legal/political dimensions of these complex relationships. Regularly scheduled health checks, online journaling, video interviews, and photos were drawn on to paint a picture of this collective experience. Join us as principal investigator and research subject, Dr. Martin Reinhardt, shares background information and outcomes of this fascinating study.